The Role of Pattern Recognition Receptor (PRR) in the Body's Defense System: A Narrative Literature Review

Each cell has receptors on the surface that specifically bind to solutes (ligands) produced during tissue damage or infection. This review aimed describe role of PRR in human body's defense system. The binding ligand its receptor results activation intracellular signaling pathways and activation. B T lymphocytes adaptive immune system have developed (that is, T-cell receptor, TCR, B-cell BCR) a broad spectrum antigens. cells involved innate resistance distinct set recognize much more limited array specific molecules. These are called pattern recognition (PRR), they molecular patterns infectious agents their products (pathogen-associated patterns, PAMP) cellular (necrosis apoptosis; pattern-associated damage, DAMPs). In conclusion, (PRR) is complex interacts with various molecules, such as PAMP DAMPs. bonds these molecules play actions immunity immunity.